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Int J Mol Sci (2021) 22(11):5876
Mechanism of Action: qualitatively similar to dextroamphetamine compared to amphetamine, the methyl side group present in methamphetamine results in a higher lipid solubility, greater penetration of the blood brain barrier, higher potency with respect to dopamine release, longer half life, and higher potential for abuse and neurotoxicity due to oxidative stress (Yamamoto & Raudensky, 2008
10.1093/ageing/afad178 64 De FeliceF
Taking the stimulants caffeine and ephedra with creatine can increase the risk of side effects
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