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It is relevant because NNMT is overactive in fat tissue during obesity

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As a general rule, IM is favored when the goal is rapid correction of a clinical deficiency, when the patient has difficulty absorbing B12 through oral or sublingual routes, or when a provider wants predictable peak serum levels

Formulated with 0.9% benzyl alcohol (9 mg/mL) as a bacteriostatic preservative, it helps inhibit microbial growth, making it ideal for repeated withdrawals when proper sterile technique is followed