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Curr Drug Targets

This method achieves significantly higher plasma concentrations compared to oral supplements, which typically have only 2-10% absorption rates.

doi: 10.1016/j.chembiol.2019.01.008 115 SchmittAXuWBucherPGrimmMKonantzMHornHet al

Most preclinical studies utilize supraphysiologic doses, alternate routes of administration and short follow-up windows that do not mimic human reproductive timelines

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