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Abbreviations GLP-1 RA: Glucagon-like peptide-1 receptor agonist MACE: Major adverse cardiovascular events HR: Hazard ratio CI: Confidence interval HER: Electronic health record ICD: International statistical classification of diseases and related health statistical classification of diseases and related health problems CPT: Current procedural terminology BMI: Body mass index MRA: Mineralocorticoid receptor antagonist ACE inhibitor: Angiotensin converting enzyme inhibitor ARB: Angiotensin II receptor blocker SGLT2 inhibitor: Sodium-glucose co-transporter 2 GFR: Glomerular filtration rate HbA1c: Hemoglobin A1c STROBE: Strengthening the reporting of observational studies in epidemiology SD: Standard deviation PS: Propensity score SMD: Standardized mean difference References Nichols, G

The first gene strongly associated with psoriasis susceptibility is HLA-Cw6, located at PSORS1 on chromosome 6p21.3 ( 3.1.2.2 Immune factors Interactions between tumor necrosis factor-alpha (TNF-), interferon-gamma (IFN-), and IL-17 induce inflammation and epidermal hyperproliferation ( 3.1.2.3 Environmental factors Beyond genetic predisposition, environmental factors significantly impact the onset, severity, and course of psoriasis ( Ultraviolet (UV) Light: Exposure to UVB radiation, a component of sunlight, is a well-established environmental trigger

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We tend to follow these guidelines, as the medications are very expensive if not covered. As effective as they are, she says, GLP-1s are not a quick fix, and theyre not for people who need or want to lose the 10-15 pounds that can accompany the transition into midlife (for those folks, Gennevs menopause-trained MDs and RDNs have many weight management strategies that can be tailored to patient goals)