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Cells can ingest cystine through the transporter xCT on the membrane surface, which in turn is reduced to cysteine for the synthesis of reduced GSH

It is particularly concentrated in the liver, where it plays a critical role in detoxification

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[DOI] [PubMed] [Google Scholar] Pero R., Angrisano T., Brancaccio M., Falanga A., Lombardi L., Natale F., Laneri S., Lombardo B., Galdiero S., Scudiero O