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Data availability Raw RNA-seq and ChIP-seq data generated in this study have been deposited in the Gene Expression Omnibus (GEO) database with accession code GSE275989

Clashes between protein and lipid atoms were reduced through 2500 conjugate-gradient minimization steps, followed by a 6 ns long MD simulation with a linearly-released positional constraint of 1 kcal mol 1 2 on protein and lipid phosphorus atoms

1A), but the effect was not maintained after 24 h (Fig

Poor Nutrition: A diet low in the precursor amino acidsspecifically cysteinemakes it difficult for the liver to synthesise enough glutathione

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