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This cardiac stress is one of the main reasons the drug is still in testing

Results may depend on factors such as: consistency with dosing schedule nutrition habits physical activity levels sleep patterns metabolic health markers individualized treatment approach Gradual increases allow individuals to balance effectiveness with comfort

I would say its not impossible, it just hasnt been studied, she added

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Last updated June 2026

Retatrutide (LY3437943) is an investigational triple-agonist drug administered as a once-weekly subcutaneous injection