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Its perhaps no surprise that semaglutide first took off in Hollywood, where many celebrities have turned to controversial methods at some point to lose weight in short time frames

Thus, more prospective clinical studies on non-diabetic obese patients are needed

A large 2026 analysis of more than 9,000 patients found that people who stopped semaglutide or tirzepatide regained an average of nearly 2 pounds a month

In fact, appetite suppression (which may feel like mild nausea) is exactly how the medication drives weight loss

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