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GSH deficiency on hepatocyte epigenetic modifying enzymes Hepatocytes treated with GCLC siRNA showed elevated Dnmt, Tet2, and Tet3, but Tet1 was downregulated, and there was no change in Tdg mRNA expression (Fig

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Postmortem human study demonstrated MPs/NPs were 730 times higher in frontal cortex than kidney or liver, with 75% of particles identified as PE (Nihart et al., 2025)

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