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CPT1A inactivation reduced cellular ATP levels and caused cell cycle arrest at G0/G1 stage, implying that ovarian cancer cells rely on CPT1A-mediated FAO for cell cycle progression (Shao et al., 2016)

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Metabolic Research2026-07-01 Retatrutide, Tirzepatide, Semaglutide: Mechanism Comparison This article explores the distinct mechanistic actions of retatrutide, tirzepatide, and semaglutide, focusing on their varying receptor agonism and implications in metabolic research

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66,67 Furthermore, oxidative stress disrupts mitochondrial membrane potential, impairs autophagy, and induces apoptosis, contributing to progressive liver damage