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In a population study on iodine deficiency and thyroid disruptors performed in children (under the age of 7 years) in Haiti, a positive association was found between exposure to perchlorate or thiocyanate and median urinary iodine levels

Other considerations documented for tirzepatide in its FDA labeling include injection-site reactions, decreased appetite, and warnings such as the risk of thyroid C-cell tumors observed in rodents (a boxed warning) and pancreatitis and gallbladder events