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GLP-1 therapy may help reduce this inflammatory burden by supporting fat loss and improving insulin sensitivity

The phenomenon can be explained as the higher positive charge of NPs results in more significant electrostatic interactions with cells

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Given the multifactorial and heterogeneous pathophysiology of tinnitus, which involves maladaptive neuroplasticity, inflammation, oxidative stress, and often comorbid psychological distress, a single-target pharmacological intervention is unlikely to be universally effective

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