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How Excess Fat Suppresses Testosterone Adipose tissue (body fat) contains the enzyme aromatase, which converts testosterone into estradiol (a form of estrogen)

It is important to note that excessive exercise (e.g., overtraining) is widely reported to decrease levels of androgens (143) and AR (144)

This is further supported by a study of the SLC19A1 variant rs1051266:G (125)

Non-normally distributed variables were reported using medians and IQRs

Network-based approaches enable reconstruction of molecular interaction networks from multi-omics data, providing insights into biological pathways underlying reproductive processes [82]

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