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10.1107/S2059798321007531

TB4 lowered oxidative stress and lipid peroxidation, boosted antioxidants, suppressed inflammation by inhibiting nuclear factor kappa B, and prevented liver fibrosis [38]

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Research demonstrates that TB-500 forms functional complexes with PINCH-1 and integrin-linked kinase (ILK) that can inhibit TNF--induced NF-B activation through blocking RelA/p65 translocation, providing rapid suppression of inflammatory transcriptional programs