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Semaglutide and tirzepatide were not designed to affect hair, but the way they work indirectly puts hair follicles at risk

[3] [4] It targets three key hormonal receptors simultaneously: the glucagon-like peptide-1 (GLP-1) receptor, the glucose-dependent insulinotropic polypeptide (GIP) receptor, and the glucagon receptor

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But the specifics of dosing, titration speed, and available dose strengths differ in ways that impact the practical experience of using each medication

Others may require medical evaluation