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The review also evaluates the evolution of professional society guidance, including the transition from the 2023 American Society of Anesthesiologists consensus-based recommendation for routine medication withholding to the 2024 multi-society guidance advocating a more individualized, risk-stratified management approach

TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death

10.1053/j.ackd.2017.05.001 47 TangX.GongX.WangQ

Not perfect, but far less waste than 4mg unused

Brain Behav Immun 20:5763

A modest caloric deficit of 500600 calories per day, as recommended by NICE for weight management, is more sustainable and less likely to cause metabolic adaptation