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2023), exerts protective effects by immobilizing toxic ions in the apoplast, strengthening cell wall integrity, modulating metal uptake, and activating antioxidant defenses

According to the filing on the ClinicalTrials.gov website, the study has an estimated start of 28 April 2023 and an estimated primary completion date of March 2025

In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]

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168 Canolol similarly reduced apoptosis via inhibition of p38 MAPK, lowering Bax levels and enhancing Bcl-2 expression in gastric mucosal cells