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Newer evidence suggests that presence of mucus plugs increases all-cause mortality in COPD patients even in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Stage 1 and proposes an early role for thiol based mucolytics for better disease outcomes (18, 19)

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Other authors studied the levels of MDA, catalase, GSH-Px, and SOD in the tissues of 10 patients with active vitiligo, 10 patients with stable vitiligo, and 20 matched healthy controls