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In the foundational study, MOTS-c treatment prevented diet-induced obesity and reversed age-dependent muscle insulin resistance in mice (Lee et al., 2015, Cell Metabolism, PMID 25738459)

Additionally, there was a significant positive correlation between the antral length by ultrasound and Bristol stool score in all cases and a distinct positive (almost significant) with the group who received KD with L-carnitine supplementation indicating that an increase in antral length was associated with higher Bristol stool score hence a softer stool consistency

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These supplements are often used as part of a daily supplement regimen

Access this chapter References and Further Reading Barnhill, R