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Common early side effects include nausea, mild abdominal discomfort, and changes in bowel habits, which generally improve within 24 weeks as the body adjusts to the medication

[2] [3] However, in April 2025, Pfizer announced it would abandon further development of danuglipron due to unpredictable liver toxicity

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[4] Users should discontinue use if they experience any signs of allergic reactions, such as redness, hives, or itchiness

Prior to the end of the treatment time point, a 12-well tissue culture plate was incubated with 1% bovine serum albumin in DMEM for 2 h