Prespecified subgroup, sensitivity and specificity analyses Subgroup analyses were conducted based on gender, age, body mass index (BMI), HbA1c, DM status (pre-existing or post-transplant), post-transplant eGFR, the presence of hypertension, proteinuria, heart failure, obesity, enrollment time, prior history of GLP-1RAs uses before transplant, and the concurrent use of medications, including ACEIs/ARBs, antidiabetic agents (insulin, metformin, dipeptidyl peptidase-4 inhibitors (DPP-4is), sodium-glucose cotransporter 2 inhibitors (SGLT2is), and immunosuppressants (steroids, cyclosporine and tacrolimus)
This dose produces meaningful results while minimizing side effect burden
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[DOI] [PubMed] [Google Scholar] 13.Oken MM, Creech RH, Tormey DC, et al
Later with each successive decade, the incidence decreased and is rare in people older than 50 years of age