Additionally, real-world pharmacovigilance data highlight sensory adverse events (particularly dysgeusia) that appear more frequently in clinical practice than in controlled trials, suggesting under recognition of taste-related disturbances in research settings (159)
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See related article by Breitzig et al G lucagon-like peptide-1 receptor agonists (GLP-1 RAs) mimic the physiological effects of native incretins insofar as they facilitate glucose-stimulated insulin secretion, decrease glucagon synthesis and release, slow gut motility, and reduce appetitive drive
The underlying mechanism is the same: altered gastric function and diaphragmatic sensitivity to medication-induced pressure changes
