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Ding, K

Lesjak M, Simin N, Srai SKS

These include: Nausea, vomiting, and diarrhoea (very common, especially during dose escalation) Reduced appetite and abdominal discomfort Constipation Risk of hypoglycaemia when used with insulin or sulphonylureas Pancreatitis and gallbladder disease have been reported Thyroid C-cell tumours have been observed in animal studies, though the relevance to humans is unknown Important safety considerations when using both treatments include: Mounjaro can reduce the effectiveness of oral contraceptives due to delayed gastric emptying

The raised flap is entirely dependent on blood flow through small vessels at its base, and any factor that compromises oxygen delivery (anaemia being a major one) puts the flap at risk

Oo AM, Nor MNM, Lwin OM, Simbak N, Adnan LHM, Rao USM