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Interestingly, clinical data from the SURMOUNT trials showed that mood improvement was dose-dependent, meaning higher doses were associated with better mood scores overall

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The therapeutic potential of GLP-1R agonists alone or in combination with other peptide agonists or other small-molecule therapeutics for the treatment of overweight/obesity and NASH is under evaluation, with a specific focus on efficacy and safety

As expected, significant amounts of the toxicant were measured in the CSF in vehicle-treated animals, reaching a 30 M concentration after 5 min of perfusion

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