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KPV is a tripeptide from -MSH with genuinely interesting preclinical anti-inflammatory data, most notably in mouse colitis models where it is taken up by the intestinal transporter PepT1 and inhibits NF-B signaling

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Compared with vehicle controls, GLP-1GIPLani yielded more than 5,411 differentially expressed genes (DEGs) in the liver, compared to only 913 and 57 DEGs induced by GLP-1GIP and Lani, respectively (Extended Data Fig

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