With activist investors bemoaning returns on R&D and M&A investment and the loss of about $17bn in revenues looming from exclusivity expiries in 20252030, the company has been culling its pipeline and looking externally for assets
Enhances Insulin Sensitivity: GLP-1 improves insulin sensitivity, particularly in muscle tissue, allowing cells to utilize glucose more efficiently for energy rather than storing it as fat
The limitation of lipidation: conversion of semaglutide from once-weekly to once-monthly dosing
Key Products: Trevogrumab, anti-myostatin antibody designed to preserve lean muscle mass that was tested in combination with semaglutide to offset GLP-1-associated muscle loss
Severe, persistent, or worsening abdominal pain
If you find yourself frequently injecting early, consider whether you would benefit from a split dosing schedule or a different injection day that works better with your routine