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The poor metabolizer phenotype has a frequency of 3%-5% in Caucasians (11,12).The most frequent variants are CYP2C9*2 (rs4917639, p.R114C) and CYP2C9*3 (rs1057910, p.I359L) alleles

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As is a highly reactive aldehyde, MDA can combine acetaldehyde (AcA) to form MAA or the MAA adduct [102]

Int J Mol Sci 21(4):1275 Gamret AC, Price A, Fertig RM, Lev-Tov H, Nichols AJ (2018) Complementary and alternative medicine therapies for psoriasis: a systematic review