When patients receive this support along with medication, they are more likely to stay adherent and make the lifestyle changes necessary for long-term success
All subjects receive tirzepatide at the maximally tolerated dose for 36 weeks
Baseline bone density testing is not routinely required for all patients but may be appropriate for those at higher risk, including postmenopausal women, older adults, individuals with prior fractures, or those with documented osteopenia or osteoporosis
Comparative efficacy of THR- agonists, FGF-21 analogues, GLP-1R agonists, GLP-1-based polyagonists, and Pan-PPAR agonists for MASLD: a systematic review and network meta-analysis
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These small changes are the earliest visible signs of the transformation that will accelerate dramatically over the coming months