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Monitoring and Dosage Adjustments When Combining These Medications Your doctor may need to increase your GLP-1 dose if you're taking prednisone, because the steroid's glucose-raising effect can blunt the GLP-1's efficacy

Shortening the interval between doses increases the amount of medication in your bloodstream beyond what was studied in clinical trials, which can significantly increase the risk of severe side effects like nausea, vomiting, and dehydration

Such agents mimic the bodys own intestinal hormone GLP1 in its mode of action, which is produced and released by the body in the digestive tract when food is consumed with the aim of effectively regulating blood glucose levels

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