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As shown in the Number of trials and Number of patients columns in the table, antidepressants were overall poorly investigated in small RCTs and with low to moderate SMDs between drug and placebo (SMD (95% CI)

The most common adverse effects of GLP-1 receptor agonistsnausea, vomiting, diarrhea, and constipationoccur in 20-50% of patients in general populations

Persistent epigastric discomfort, black stools, or any sign of bleeding is described as warranting prompt clinical evaluation rather than waiting it out

According to FDA prescribing information, genital mycotic infections occur in approximately 10-15% of women and 3-7% of men taking SGLT2 inhibitors, with rates varying by specific agent, patient sex, and circumcision status in men, representing a three- to fourfold increase compared to placebo

Alternative Names: BPC-157 (Body Protection Compound-157)