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In addition, by improving mitochondrial function through AMPK/SIRT1 signaling, GLP-1RAs reduce ROS generation, indirectly lowering DNA and RNA damage burden

Specific indications for Lp(a) measurement are: premature onset of cardiovascular disease, the lack of expected effect of statin therapy, and the need for better risk stratification in moderate- to high-risk individuals [50]

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PMID: 27 ChenK.JinH

It is administered as a once-weekly injection, making it a convenient option for patients struggling with obesity

Its also important to note that everyones body reacts differently to medication