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Reduces appetite and increases satiety to support sustainable weight management Enhances insulin sensitivity and reduces post-meal glucose spikes to help maintain healthy glucose levels Acts on brain pathways that control hunger and food intake Improved weight and metabolic control may help reduce risk factors associated with cardiometabolic disease Semaglutide is a GLP-1 receptor agonist that mimics a natural hormone involved in regulating appetite, insulin secretion, and blood sugar levels

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Special Populations and Considerations Certain subgroups of adolescents may derive particular benefit from GLP-1 RA therapy or require special consideration

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rhamnosus GG (LGG), thereby demonstrating the potential for translocation and systemic spread