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Tagline: GLP-1 Drugs: Game-changing medicine or a costly craze
Though newer to the scene, early indications suggest it might offer similar cardiovascular protections
Kisseleva T, Brenner D
and internationally, and we intend to build on this positive momentum in the quarters ahead. Pfizer analyst ratings and price targets are at MarketBeat
Taken together, these observations would support the hypothesis that GLP-1R can internalize by more than one mechanism and that regions other than the C-terminal tail may be involved in this process
Lipid profile improvements (TRIUMPH-4): Non-HDL cholesterol: Clinically meaningful reduction Triglycerides: Significant reduction hsCRP (inflammatory marker): Significant reduction HDL cholesterol: Not significantly improved (consistent with Phase 2 findings) The triglyceride reduction is particularly notable and likely related to glucagon receptor activation, which enhances fat oxidation
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