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GPER activation in females more effectively promotes fatty acid oxidation, reducing adiposity

Chemosensitivity enhancement by two different shRNAs to PGRMC1 was seen also in HCT116 cells and human hepatoma HuH7 cells (Supplementary Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Strbe S., Gojkovic S., Krezic I., Zizek H., Vranes H., Barisic I., Strinic D., Orct T., Vukojevic J., Ilic S., et al

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Once absorbed, glucosinolate-derived isothiocyanates (like sulforaphane) are promptly conjugated to glutathione by a class of phase II detoxification enzymes known as glutathione S -transferases (GSTs) in the liver, and then sequentially metabolized in the mercapturic acid pathway ( Figure 2 )

From the beginning of the first treatment, all mice were weighed and tumor size was measured with vernier calipers every 2 days