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In contrast, although BFA treatment induced SLC7A11 to be stuck in the ER, only ~15% of VRK-KO cells returned SLC7A11 to the Golgi 4 h after BFA removal

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Through this action, omega-3 indirectly inhibits multiple pro-cancer signaling pathways, including the EGFR-mediated RAS/MAPK cascade and the PI3K/Akt survival pathway (59)