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Considering that Novo fully acquired Emisphere and its Eligen SNAC platform, the availability and licensing of SNAC could become a major barrier for generic oral semaglutide

Currently, there are synthetic (made in a lab) versions of thyroid replacement hormones, like Synthroid and its generics, which most hypothyroid patients take

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Intervention 1 Intervention 2 Intervention 3 Intervention 4 Intervention 5 Not provided Anticipated Start Date Not provided Actual Start Date 2018-11-29 Anticipated Date of Last Follow-up 2021-03-05 Estimated Primary Completion Date Not provided Estimated Completion Date Not provided Actual Primary Completion Date 2019-12-16 Actual Completion Date 2020-01-17 Age Cohort Genders Accepts pregnant individuals Unspecified Accepts lactating individuals Unspecified Accepts healthy individuals No Inclusion Criteria: * Male or female, aged 18-75 years (both inclusive) at the time of signing informed consent * Diagnosed with type 2 diabetes mellitus greater than or equal to 180 days prior to the day of screening * HbA1c of 7.0-9.5% (53-80 mmol/mol) (both inclusive) as assessed by central laboratory * Stable daily dose(s) for 90 days prior to the day of screening of any of the following antidiabetic drug(s) or combination regime(s): Any metformin formulations greater than or equal to 1500 mg or maximum tolerated or effective dose (as documented in subject's medical record) OR Any metformin formulations greater than or equal to 1500 mg or maximum tolerated or effective dose (as documented in subject medical record) with Dipeptidyl peptidase-4 inhibitor (DPP4i) (greater than or equal t Not provided Interventional (clinical trial) 247 Randomized Parallel Assignment Not provided Quadruple-blind masking Not provided Treatment NCT05823948 Phase III Completed Novo Nordisk A/S This study looks at how a person with type 2 diabetes can be treated with insulin icodec and a flash glucose monitor (a small sensor inserted under the skin to measure blood sugar all the time)