Appetite Control and Craving Reduction Many participants reported: Feeling full sooner Reduced cravings, especially for high-calorie foods Less frequent blood sugar dips The combination of slower digestion and steadier blood sugar regulation tends to make eating patterns more consistent and manageable
Where the compounds differ is in the primary medication
Phase 2 trial data have explored weekly subcutaneous doses ranging from 1 mg to 12 mg, administered via a gradual escalation schedule
Clinical Trial Evidence and Findings in Female Participants Phase 2 trial data (Jastreboff et al., NEJM, 2023) showed dose-dependent weight reduction and metabolic improvements, but sex-disaggregated results were not published, so female-specific efficacy cannot yet be confirmed
Both compounds attenuated alcohol discrimination in a manner consistent with the semaglutide findings
When considering which GLP-1 medication is best for you, the cost is a significant factor to explore