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In these cases, gabapentin levels can rise to harmful levels if dosing is not properly adjusted, potentially leading to side effects that may indirectly affect kidney health

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Proc Natl Acad Sci USA 1991;88:36336

3.7 Endoplasmic reticulum stress ERS refers to the disruption of normal functioning and homeostasis within the endoplasmic reticulum (ER) of cells, resulting from the accumulation of unfolded or misfolded proteins and an imbalance between protein folding capacity and protein load