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Efficacy of Tirzepatide vs
Wegovy is administered as a once-weekly subcutaneous injection , typically into the abdomen, thigh, or upper arm
GLP-1 receptors sit in the pancreas (driving glucose-dependent insulin secretion and suppressing glucagon), in the hypothalamus (appetite suppression and satiety), in the GI tract (slowed gastric emptying), and on cardiomyocytes in the heart
RA often limits peoples ability to perform daily tasks, like walking, climbing stairs, or even gripping objects
Advantages of injectable delivery include well-established protocols, extensive clinical trial data using this method, and once-weekly rather than daily administration