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Early cost containment through dosing strategy, combined with genetic and biomarker context, enables more informed decisions about continuing treatment, adjusting formulation, or exploring alternatives if response is suboptimal

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Sensors Actuators B 232:5259 Wei J, Guo Y, Li J, Yuan M, Long T, Liu Z (2017) Optically active ultrafine AuAg alloy nanoparticles used for colorimetric chiral recognition and circular dichroism sensing of enantiomers

UK prescribers and patients now have substantial real-world experience with titration, injection technique, missed-dose rules, and follow-up, alongside the SURPASS trial programme that supported licensing

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Digestion parameters were set to trypsin allow P with an allowance of four missed cleavages