The Endocrine Society's 2022 clinical practice guideline on type 2 diabetes management states: "Clinicians should systematically review concomitant medications that affect renal function or compete for renal tubular secretion when prescribing metformin" [15]
GLP-1 medications may support appetite control and weight loss, but they work best as part of a broader plan
Interaction of Janus kinases JAK-1 and JAK-2 with the insulin receptor and the insulin-like growth factor-1 receptor
Patients: A total of 397 adult patients with T2D inadequately controlled on basal insulin with or without metformin were randomized to once-weekly Ozempic injection 0.5 mg (n=132), Ozempic injection 1 mg (n=131), or placebo (n=133)
Brand-name drugs used to treat myriad conditions, from diabetes to heart disease, cost more in the US, because the Medicare program historically was prohibited from negotiating drug prices
Anti-inflammatory effects often manifest first, typically within 1 to 3 days
