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It's important to note though: creatine loading isn't a bad thing just because it can lead to water retention

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Detoxifies the liver Glutathione is produced by the liver and is involved in many blood processes, from tissue-building repair to making chemicals and proteins needed by the body and immune system function

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Mannowetz N, Kartarius S, Wennemuth G, Montenarh M (2010) Protein kinase CK2 and new binding partners during spermatogenesis