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Glucagon-like peptide-1 receptor agonists and risk for gastroesophageal reflux disease in patients with type 2 diabetes : a population-based cohort study
32 Thereby, they stimulate insulin secretion and reduce glucagon secretion in a glucose-dependent manner, both effects contributing to the glucose-lowering activity (Figure 1)
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In contrast to findings in DIO mice, semaglutide did not significantly alter J O 2 , J ATP, or the resulting P/O ratio in either sex, indicating no improvement in mitochondrial efficiency
Treatment with semaglutide further amplified the number of autophagosomes in H/R-exposed cells, suggesting that semaglutide may provide protective effects against hypoxic damage by enhancing autophagy
