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In patients who do not respond to treatment, the value of continuous enteral feeding and especially of surgical re-intervention and pancreatic resection is uncertain (statements 5658 and 6062) and a conservative, non-surgical approach is recommended (statement 59)
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This mechanism also acts as a vital "on/off" switch for cellular signaling, modulating enzyme activity and controlling how DNA binds to transcription factors during an immune response
Nach der Cyclisierung wurde das Peptidharz gewaschen und das Peptid von dem Harz und brig gebliebenen Schutzgruppen unter Verwendung von Trifluoressigsure (TFA) in Gegenwart von Wasser und 1,2-Ethandithiol (EDT) abgespalten
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