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Renin-angiotensin system (RAS) inhibitors and nonsteroidal MRA are beneficial for treatment of CKD but may not fully block harmful effects of aldosterone

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There are some dramatic left-tail-risk scenariosfor example, all people with above-average body mass index (BMI) take GLP-1 medications and stick to the prescribed regimen (including changing food habits per doctor recommendations) for a prolonged period

283 299 These have included monotherapy with standard interferons 285 290 leading to overall SVR rates of 33% to 37% with rates of 26% to 31% in persons with genotype 1 infection 285 , 286 but associated with high dropout rates

Wang G, Su Z, Li H, Xiao L, Li C, Lian G

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