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Hemodynamic effect of a single dose of glucagon-like peptide 1 receptor (GLP-1R) agonist liraglutide in patients with diabetic kidney disease

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Besides, GLP-1 receptors are also expressed in the human choroid plexus, and the GLP-1-RA exenatide was reported to reduce intracranial pressure in a rodent model as well as in a pilot study on 15 pwIIH [14, 15]

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AI-enabled in silico approaches, in tandem with high-throughput target binding assays (e.g., small-molecule microarrays) and phenotypic screens (perhaps using cAMP+ as a readout), may further uncover some of these incredibly useful molecules