In addition to GLP-1R agonists, orally administrated DPP4-inhibitors, e.g., sitagliptin and saxagliptin , which are known to potentiate the effect of endogenous GLP-1 by inhibiting its degradation, have also been clinically studied as protective agents against retinopathy (Chung et al., 2016), Alzheimers disease (Isik et al., 2017), and Parkinsons disease (Svenningsson et al., 2016) in T2D patients, although DPP4-inhibitors cannot cross the blood-brain barrier (Mousa and Ayoub, 2019)
A typical article breaks down the topic into easy-to-understand language and then explains the science of it (along with citations and links to the sources)
BPC 157 (10 g/kg, 10 ng/kg) was given immediately after NSAIDs administration, intraperitoneally (aspirin, diclofenac, paracetamol, ibuprofen, celecoxib) or intragastrically (aspirin, paracetamol) while controls received an equivolume (5 ml/kg) of saline
Bananas have a moderate GI, which means they can cause a slower increase in blood sugar compared to high-GI foods
Ryan, C.A
GLP-1RA appears advantageous in this regard
