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One peptide that has gained attention in sleep and wellness conversations is DSIP, short for delta sleep-inducing peptide

Since semaglutide delays stomach emptying, keeping it in your system raises the risk of aspiration while under anesthesia

Adv Ther 39(9):41144130 Matza LS, Cutts KN, Stewart KD, Norrbacka K, Garca-Prez LE, Boye KS (2021) Health state utilities associated with treatment process for oral and injectable GLP-1 receptor agonists for type 2 diabetes

doi: 10.1210/jcem.82.5.3943 121 AitmanTJRaffertyBCoyDLynchSSClaytonRN

While the papers authors note that many of those improvements were due to taking weight off the affected knees, they also postulate that semaglutides known anti-inflammatory effects played a role as well

The result is skin that looks deflated rather than refreshed