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B12 tablets are generally well-tolerated with minimal side effects

As individuals age, the ability of the body to absorb B12 will diminish

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

Slow IV injection is an option when immediate availability of the vitamins is desired or if the patient is already receiving IV fluids

When utilizing sonication methods for preparing injectable solutions, it is important to consider factors such as type of solvent, temperature and duration of exposure, power intensity, sample concentration, and size distribution of particles in order to optimize the efficacy and safety of these drugs prior to administration

Several commenters agreed that while some proposals may be useful, CMS should focus on policies that directly help patients understand the costs of their care rather than increasing administrative requirements on hospitals