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KPV is a short peptide derived from alpha-MSH (melanocyte-stimulating hormone) sequences and is studied for anti-inflammatory signaling, including effects on cytokines (chemical messengers of inflammation) and gut inflammation models
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This is arguably the case for the -3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which have been studied extensively for their ability to lower metabolic disease risk (Kris-Etherton et al., 2003
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Abbreviations CAT: Catalase COMT: Catechol-O-methyltransferase Fcx: Frontal cortex GABA: Gamma-aminobutyric acid GPx: Glutathione peroxidase GR: Glutathione reductase HIP: Hippocampus HPLC: High-performance liquid chromatography LDH: Dehydrogenase leakage MAO: Monoamine oxidase 1MeTIQ: 1-Methyl-1,2,3,4-Tetrahydroisoquinoline MK-801: Dizocilpine MPP + : 1-Methyl-4-phenylpyridinium ion MTT: M tetrazolium NMDA: N-methyl-D-aspartate PD: Parkinsons disease PPI: Prepulse inhibition ROS: Reactive oxygen species SOD: Superoxide dismutase References Adams B, Moghaddam B (1998) Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine
